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Post by JHam on Dec 8, 2014 23:10:00 GMT
Clarification: "Meaningful" as in having a major impact on share price (in context of thread subject). I expect the next major data catalyst in the eye trials will be Phase 2 data and it's going to be a long wait. Top-line Phase 1 data may prove to be a catalyst in 2015, but do people really expect it to exceed or differ much from market expectations following the Lancet results? Phase 2 data may be a long-ish wait. But there's more going on than just the eye p2 trials. I still think that we will see some news accompany the uplist to give the new share holders some reassurance of their purchase. "Expectations following Lancet results"? Not really sure I understand where you are coming from. Market expectations prior to the results saw $12. Then, in-conjunction of results, the company released news of the shelf, we rallied to $9, then fell. Post Lancet has had a dark cloud over the company for some regarding the cash situation. If the company released great news with not other bad news to follow I expect to see a rapid increase in PPS. Of course there will be some erosion, but with no bad news, the general trend will be north. What are you expecting to happen from now, we just float in the $6-$7 range until commercialization? Wotton's comment, and now it is on the slide, about partnering the blood program is what has my attention right now more than anything.
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Post by tradeup on Dec 8, 2014 23:46:35 GMT
"Expectations following Lancet results"? Not really sure I understand where you are coming from. Market expectations prior to the results saw $12. Then, in-conjunction of results, the company released news of the shelf, we rallied to $9, then fell. Post Lancet has had a dark cloud over the company for some regarding the cash situation. If the company released great news with not other bad news to follow I expect to see a rapid increase in PPS. Of course there will be some erosion, but with no bad news, the general trend will be north. This is an over-simplification of what actually transpired. Market expectations were overblown for Phase 1 data and the expectation was to land NEJM (highest impact factor journal), which never happened. Lanza dumped, the resolution of the SEC suit was PR'd, and the shelf was filed. And when the paper was finally released, the results didn't seem to meet market expectations. Great safety profile with hints of efficacy, but the market has spoken: sufficient data against established endpoints will be needed in a well controlled Phase 2 for there to be a meaningful impact on the share price. You have to keep absolute valuation in mind in terms of clinical progress and milestones. Relative to peers, it's not cheap.
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Post by CM kipper007 on Dec 8, 2014 23:57:55 GMT
"Expectations following Lancet results"? Not really sure I understand where you are coming from. Market expectations prior to the results saw $12. Then, in-conjunction of results, the company released news of the shelf, we rallied to $9, then fell. Post Lancet has had a dark cloud over the company for some regarding the cash situation. If the company released great news with not other bad news to follow I expect to see a rapid increase in PPS. Of course there will be some erosion, but with no bad news, the general trend will be north. This is an over-simplification of what actually transpired.Market expectations were overblown for Phase 1 data and the expectation was to land NEJM (highest impact factor journal), which never happened. Lanza dumped, the resolution of the SEC suit was PR'd, and the shelf was filed. And when the paper was finally released, the results didn't seem to meet market expectations. Great safety profile with hints of efficacy, but the market has spoken: sufficient data against established endpoints will be needed in a well controlled Phase 2 for there to be a meaningful impact on the share price. You have to keep absolute valuation in mind in terms of clinical progress and milestones. Relative to peers, it's not cheap. That is exactly my point. You are asking if we think the market will see things differently with the expectations following The Lancet, leaving out a lot of details that knocked the pps hard. Are you saying that every time OCAT is to release news it will be over hyped? If we get good news that isn't shadowed by anything bleak, then of course people expect to see a rally. As for peers, this has been discussed elsewhere, but AAVL is doing really well right now. I understand developing a product costs a whack of cash, but we have more potential applications that AAVL does.
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Post by tradeup on Dec 9, 2014 0:14:49 GMT
This is an over-simplification of what actually transpired.Market expectations were overblown for Phase 1 data and the expectation was to land NEJM (highest impact factor journal), which never happened. Lanza dumped, the resolution of the SEC suit was PR'd, and the shelf was filed. And when the paper was finally released, the results didn't seem to meet market expectations. Great safety profile with hints of efficacy, but the market has spoken: sufficient data against established endpoints will be needed in a well controlled Phase 2 for there to be a meaningful impact on the share price. You have to keep absolute valuation in mind in terms of clinical progress and milestones. Relative to peers, it's not cheap. That is exactly my point. You are asking if we think the market will see things differently with the expectations following The Lancet, leaving out a lot of details that knocked the pps hard. Are you saying that every time OCAT is to release news it will be over hyped? If we get good news that isn't shadowed by anything bleak, then of course people expect to see a rally. As for peers, this has been discussed elsewhere, but AAVL is doing really well right now. I understand developing a product costs a whack of cash, but we have more potential applications that AAVL does. I don't expect OCAT to trade as irrationally on the Nasdaq as it has on the OTC if that's what you are asking. AAVL is an outlier (on the high-end) in terms of peer comparison. Similar market, but it's also a gene therapy company and the entire sector has been on a tear. Look at BlueBird Bio's results today, another gene therapy company. AAVL has an established pharma partnership and expects top-line P2 data by mid-2015 which could be a significant catalyst to their entire platform.
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Post by rickrick on Dec 9, 2014 0:52:42 GMT
We could also change the thread title to read "Daily Discussion" if you want. I think that would take care of it, thanks.
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Post by jeff on Dec 9, 2014 1:32:26 GMT
This is an over-simplification of what actually transpired.Market expectations were overblown for Phase 1 data and the expectation was to land NEJM (highest impact factor journal), which never happened. Lanza dumped, the resolution of the SEC suit was PR'd, and the shelf was filed. And when the paper was finally released, the results didn't seem to meet market expectations. Great safety profile with hints of efficacy, but the market has spoken: sufficient data against established endpoints will be needed in a well controlled Phase 2 for there to be a meaningful impact on the share price. You have to keep absolute valuation in mind in terms of clinical progress and milestones. Relative to peers, it's not cheap. That is exactly my point. You are asking if we think the market will see things differently with the expectations following The Lancet, leaving out a lot of details that knocked the pps hard. Are you saying that every time OCAT is to release news it will be over hyped? If we get good news that isn't shadowed by anything bleak, then of course people expect to see a rally. As for peers, this has been discussed elsewhere, but AAVL is doing really well right now. I understand developing a product costs a whack of cash, but we have more potential applications that AAVL does. With respect Kip--because I have a lot of respect for you -- I read Tradeup's comment about results not meeting market expectations to be an objective observation--that is, an observation that really doesn't say much about what should have happened in the wake of the Lancet article, right? But only says what did happen. Which is a little different than intimating that Tradeup's view is that OCAT's news releases will be over-hyped, and thus won't move the pps in the magnitude we might expect or hope for. I, for one, thought the publication would have moved the needle more, and more importantly, more-permantly, than it did. If I'm understanding Tradeup's analysis correctly, he's saying that the "market" didn't see things the same way as I did. I'm a data point in the market. All of us are. It raises a really interesting point or question. What comprises the "market" for OCAT? Is it us, posters and lurkers on chat boards? Is it a much-broader universe of investors? Who is the market for OCAT? And when good news hits, is there an informed market that can express an efficient valuation for the company? Some posters clearly follow an efficient market theory of valuation. Others believe in disruption. Very interesting, and potentially lucrative, I guess, to be able to correctly answer that question. Myself? No idea who's got it right at this point in OCATA's history. Makes me nervous, because I'm betting one way, and not the other.
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Post by Keybridge - Cult Member 003 on Dec 9, 2014 1:43:05 GMT
This is an over-simplification of what actually transpired.Market expectations were overblown for Phase 1 data and the expectation was to land NEJM (highest impact factor journal), which never happened. Lanza dumped, the resolution of the SEC suit was PR'd, and the shelf was filed. And when the paper was finally released, the results didn't seem to meet market expectations. Great safety profile with hints of efficacy, but the market has spoken: sufficient data against established endpoints will be needed in a well controlled Phase 2 for there to be a meaningful impact on the share price. You have to keep absolute valuation in mind in terms of clinical progress and milestones. Relative to peers, it's not cheap. That is exactly my point. You are asking if we think the market will see things differently with the expectations following The Lancet, leaving out a lot of details that knocked the pps hard. Are you saying that every time OCAT is to release news it will be over hyped? If we get good news that isn't shadowed by anything bleak, then of course people expect to see a rally. As for peers, this has been discussed elsewhere, but AAVL is doing really well right now. I understand developing a product costs a whack of cash, but we have more potential applications that AAVL does. Although it's routine or conventional to make peer comparison's for stocks, and AAVL looks like the best fit, I actually don't believe there are any public-company biotechs that a comparison can be made. OCAT has a multiple pipeline of cell based treatments over broad range of indications; on the verge of a JV with GE and perhaps for treatment(s) in the veterinary space, and is a front runner in cell therapy science - certainly among small and mid cap stocks. If you compiled a side by side chart of small cap biotech's at OCAT's stage of development, and the categories were size of pipeline; number of potential and existing indications; size of markets for those indications, likelihood of near term JV, and time to market taking into account the potential for accelerated approvals, there really are no good comparisons. That's not to say that day-one of the listing the stock becomes a rocket ship, but over a reasonable period of time, these factors find themselves into the stock's market cap. What's the value of OCAT in 2Q15 when a platelet JV is announced? Does the market ignore that possibility, especially since the company has offered guidance that some form of partnership is expected by then?
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django
Junior Member
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Post by django on Dec 9, 2014 1:44:33 GMT
otcshortreport.com/index.php?index=ocat&action=view#close47% of the trading volume in OCATA today was short selling. Amazing that the PPS actually went up a bit. Imagine where the share price would be if we weren't running into headwinds like this. Getting away from Lincoln should help, because those cheap shares won't be dumped into the market every day.
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Post by Keybridge - Cult Member 003 on Dec 9, 2014 1:48:43 GMT
That's the OTC market for ya. It's crazy - but good; all those shorts have to cover sometime. (And most of those shorts are now at a loss.)
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Post by iamwhatiam on Dec 9, 2014 2:17:57 GMT
That's the OTC market for ya. It's crazy - but good; all those shorts have to cover sometime. (And most of those shorts are now at a loss.) That short volume doesn't necessarily mean that all those shorts are still holding at the end of the day does it? Couldn't a lot of that short volume be intra-day flippers getting in and out of short positions for a few pennies? Meaning they're not holding that short position overnight. If they are all holding overnight, then there are a lot of folks who think OCAT's pps will drop soon, which would cause a nice short squeeze if they're wrong, and a lot of smiles for them if they are right. Conversely, if they are not holding overnight, that maybe speaks to more confidence that the current pps will hold, but it also means less of a short squeeze if the price moves up. Of course, not holding a short position overnight might also not speak of any confidence whatsoever, because it's just what day traders do, get in after 9:30 am then out by 4 pm.
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pata
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Post by pata on Dec 9, 2014 2:19:41 GMT
[ ... ] But it is interesting that OCAT is going after later stage patients with GA as their primary target market, not earlier stage patients as many here (including me) originally thought based on prior company statements. Not sure why that change in direction, as all commentary prior to the release of the Phase 2 endpoints was that earlier stage patients was the target. Perhaps they are segmenting the markets deliberately -- that is, they target for direct sales a much smaller market that they can handle the supply for themselves, while leaving the indications for which there is a much larger market to a future partnership with a large pharmaceutical corporation that has the wherewithal to market, manufacture, and distribute the treatment?
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Post by Keybridge - Cult Member 003 on Dec 9, 2014 2:34:24 GMT
That's the OTC market for ya. It's crazy - but good; all those shorts have to cover sometime. (And most of those shorts are now at a loss.) That short volume doesn't necessarily mean that all those shorts are still holding at the end of the day does it? Couldn't a lot of that short volume be intra-day flippers getting in and out of short positions for a few pennies? Meaning they're not holding that short position overnight. If they are all holding overnight, then there are a lot of folks who think OCAT's pps will drop soon, which would cause a nice short squeeze if they're wrong, and a lot of smiles for them if they are right. Conversely, if they are not holding overnight, that maybe speaks to more confidence that the current pps will hold, but it also means less of a short squeeze if the price moves up. Of course, not holding a short position overnight might also not speak of any confidence whatsoever, because it's just what day traders do, get in after 9:30 am then out by 4 pm.
Probably not flipping - the trading appears too narrow. Never know what's behind the curtain, but it could be hedging or trading in anticipation of a weak offering, and/or downright manipulation. If I had to guess, these are covered shorts to either hedge existing large positions and/or to trade on volatility. Because there is no liquid option market for OTC stocks, it makes sense to me that during a period of uncertainty there is a rise in shorting. But if these are not covered shorts - someone(s) is willing to lose dollars for the opportunity to make nickels.
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Post by jeff on Dec 9, 2014 2:48:55 GMT
CM kipper007
"Are you saying that every time OCAT is to release news it will be over hyped? "
I think I may have posted my unusually insightful and unassailable remarks in a manner that they might be ascribed, to his dismay, to Kipper--Cultist 00-whatever. Also, my comments may not have been very insightful, useful, or anything other than irritating. So don't blame Kipper-the-Third-Cultist. I was trying to respond to him, not put words in his mouth.
BALD JHAM the FIRST--why is this so hard for me? I think I'm too old, although young, to figure out how to post. So what follows is what I said, not what Kipper said, and Kipper i apologize for unintentionally hijacking your thoughtful and well-reasoned response to Trade-up. This is what I meant to say to the rest of the (small) OCTA world:
With respect Kip--because I have a lot of respect for you -- I read Tradeup's comment about results not meeting market expectations to be an objective observation--that is, an observation that really doesn't say much about what should have happened in the wake of the Lancet article, right? But only says what did happen. Which is a little different than intimating that Tradeup's view is that OCAT's news releases will be over-hyped, and thus won't move the pps in the magnitude we might expect or hope for.
I, for one, thought the publication would have moved the needle more, and more importantly, more-permantly, than it did. If I'm understanding Tradeup's analysis correctly, he's saying that the "market" didn't see things the same way as I did. I'm a data point in the market. All of us are.
It raises a really interesting point or question. What comprises the "market" for OCAT? Is it us, posters and lurkers on chat boards? Is it a much-broader universe of investors? Who is the market for OCAT? And when good news hits, is there an informed market that can express an efficient valuation for the company? Some posters clearly follow an efficient market theory of valuation. Others believe in disruption. Very interesting, and potentially lucrative, I guess, to be able to correctly answer that question.
Myself? No idea who's got it right at this point in OCATA's history. Makes me nervous, because I'm betting one way, and not the other.
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Post by forthefuture on Dec 9, 2014 2:52:05 GMT
otcshortreport.com/index.php?index=ocat&action=view#close47% of the trading volume in OCATA today was short selling. Amazing that the PPS actually went up a bit. Imagine where the share price would be if we weren't running into headwinds like this. Getting away from Lincoln should help, because those cheap shares won't be dumped into the market every day. If the offering closes, and OCAT release some strong, unexpected news, the short squeeze could be a thing of beauty to watch.
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Post by dayanand33 on Dec 9, 2014 2:56:03 GMT
That is exactly my point. You are asking if we think the market will see things differently with the expectations following The Lancet, leaving out a lot of details that knocked the pps hard. Are you saying that every time OCAT is to release news it will be over hyped? If we get good news that isn't shadowed by anything bleak, then of course people expect to see a rally. As for peers, this has been discussed elsewhere, but AAVL is doing really well right now. I understand developing a product costs a whack of cash, but we have more potential applications that AAVL does. Although it's routine or conventional to make peer comparison's for stocks, and AAVL looks like the best fit, I actually don't believe there are any public-company biotechs that a comparison can be made. OCAT has a multiple pipeline of cell based treatments over broad range of indications; on the verge of a JV with GE and perhaps a treatment(s) in the veterinary space, and is a front runner in the cell therapy space - certainly among small and mid cap stocks. If you compiled a side by side chart of small tech biotech's at OCAT's stage of development, and the categories were size of pipeline; number of potential and existing indications; size of markets for those indications, likelihood of near term JV, and time to market taking into account the potential for accelerated approvals, there really are no good comparisons. That's not to say that day-one of the listing the stock becomes a rocket ship, but over a reasonable period of time, these factors find themselves into the stock's market cap. What's the value of OCAT is 2Q15 when a platelet JV is announced? Does the market ignore that possibility, especially since the company has offered guidance that some form of partnerships is expected by then? I am inclined to think that STEM is closer peer of Ocata than AAVL. Both are based on Stem cell technology and targeting AMD and are nearly at the same stage of FDA trials. The intention is to not to debate on who is better (stem or ocata) but to make the case that Ocata does not appear to be undervalued when compared to its close peer.
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Post by Whidbeygal CM 20/20 on Dec 9, 2014 2:56:10 GMT
"Expectations following Lancet results"? Not really sure I understand where you are coming from. Market expectations prior to the results saw $12. Then, in-conjunction of results, the company released news of the shelf, we rallied to $9, then fell. Post Lancet has had a dark cloud over the company for some regarding the cash situation. If the company released great news with not other bad news to follow I expect to see a rapid increase in PPS. Of course there will be some erosion, but with no bad news, the general trend will be north. This is an over-simplification of what actually transpired. Market expectations were overblown for Phase 1 data and the expectation was to land NEJM (highest impact factor journal), which never happened. Lanza dumped, the resolution of the SEC suit was PR'd, and the shelf was filed. And when the paper was finally released, the results didn't seem to meet market expectations. Great safety profile with hints of efficacy, but the market has spoken: sufficient data against established endpoints will be needed in a well controlled Phase 2 for there to be a meaningful impact on the share price. You have to keep absolute valuation in mind in terms of clinical progress and milestones. Relative to peers, it's not cheap.
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Post by Whidbeygal CM 20/20 on Dec 9, 2014 3:00:44 GMT
Oops. I posted before I added my opinion to the quote.
I am not sure the data was not exceptional------I believe it was. We have to remember the market tanked (wasn't it about 400 pts) on the day it was released? Ebola absolutely ruled all headlines, news stories and media.
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django
Junior Member
Posts: 68
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Post by django on Dec 9, 2014 3:07:26 GMT
Tracking daily activity, I noticed some days where manipulators were buying one share at a time, at a penny less each time. There was a one-hour period about a month ago where somebody traded 70 times in one hour, each trade being just a single share. I'd be willing to bet those guys don't even know anything about the fundamentals of the companies they trade in-- they are just playing with numbers.
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Post by CM kipper007 on Dec 9, 2014 5:36:23 GMT
CM kipper007 "Are you saying that every time OCAT is to release news it will be over hyped? " I think I may have posted my unusually insightful and unassailable remarks in a manner that they might be ascribed, to his dismay, to Kipper--Cultist 00-whatever. Also, my comments may not have been very insightful, useful, or anything other than irritating. So don't blame Kipper-the-Third-Cultist. I was trying to respond to him, not put words in his mouth. BALD JHAM the FIRST--why is this so hard for me? I think I'm too old, although young, to figure out how to post. So what follows is what I said, not what Kipper said, and Kipper i apologize for unintentionally hijacking your thoughtful and well-reasoned response to Trade-up. This is what I meant to say to the rest of the (small) OCTA world: With respect Kip--because I have a lot of respect for you -- I read Tradeup's comment about results not meeting market expectations to be an objective observation--that is, an observation that really doesn't say much about what should have happened in the wake of the Lancet article, right? But only says what did happen. Which is a little different than intimating that Tradeup's view is that OCAT's news releases will be over-hyped, and thus won't move the pps in the magnitude we might expect or hope for. I, for one, thought the publication would have moved the needle more, and more importantly, more-permantly, than it did. If I'm understanding Tradeup's analysis correctly, he's saying that the "market" didn't see things the same way as I did. I'm a data point in the market. All of us are. It raises a really interesting point or question. What comprises the "market" for OCAT? Is it us, posters and lurkers on chat boards? Is it a much-broader universe of investors? Who is the market for OCAT? And when good news hits, is there an informed market that can express an efficient valuation for the company? Some posters clearly follow an efficient market theory of valuation. Others believe in disruption. Very interesting, and potentially lucrative, I guess, to be able to correctly answer that question. Myself? No idea who's got it right at this point in OCATA's history. Makes me nervous, because I'm betting one way, and not the other. Thanks for the posts Jeff. I managed to understand what you were saying in the first one though. Yes, the who is the market question is good, but it is also changing. When was the last time we had third parties promote us? Piper J. and co must see something good here. I am very excited about that. But regarding the movement of the needle, and maybe I didn't stress this in my other post, was that the company had such a strong head wind against it. The court case, the legacy issues of the CEO, the money situation, negative articles, the constant draw from Lincoln. All those things, and still the market bought in and basically doubled the value of the company, albeit a little premature. Now the company is validated. It has amazing safety and (I think amazing) data results peer-reviewed. All the other crap is out of the way, and in the next few days there will hopefully be a positive balance sheet. On this forum, those that post, we already see people in for the long haul, but there are others patiently sat waiting their entry point too. I'd love to give Jck and co. a shove to jump in to see what will happen, but he is waiting to the 11th hour before he does. So with people waiting for their time to come in, good news from the company going forward should be able to keep some of those gains, even with people trading off the peaks. All, just my viewpoint, just another datapoint
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Post by iamaverb on Dec 9, 2014 15:31:19 GMT
The first hour of trading is over and we are down 4.69%, and I am anxious to see what will transpire next. Are we under a short attack or was this just rookie hour?
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